{"id":89,"date":"2016-05-24T19:16:38","date_gmt":"2016-05-24T19:16:38","guid":{"rendered":"http:\/\/www.expofuturo.cl\/?p=89"},"modified":"2022-08-20T01:30:45","modified_gmt":"2022-08-20T01:30:45","slug":"ramon-perez","status":"publish","type":"post","link":"https:\/\/www.expofuturo.cl\/index.php\/2016\/05\/24\/ramon-perez\/","title":{"rendered":"Ram\u00f3n P\u00e9rez"},"content":{"rendered":"

Ram\u00f3n P\u00e9rez N\u00fa\u00f1ez – Bio\"RP\"<\/a>quimico<\/p>\n

Grados Acad\u00e9micos<\/h3>\n

1999-2005 Estudios Universitarios
\nFacultad de Ciencias Qu\u00edmicas y Farmac\u00e9uticas
\nUniversidad de Chile, Licenciatura en Bioqu\u00edmica.
\nDiciembre, 2005 Grado: Licenciado en Bioqu\u00edmica
\n2006-2007 Memoria de T\u00edtulo
\n\u201cRegulaci\u00f3n de la Expresi\u00f3n del Receptor Tipo Toll 4 (TLR4) por el Factor de Necrosis Tumoral \u03b1 y Dexametasona\u201d<\/p>\n

2011-2015 Programa Doctorado en Bioqu\u00edmica
\nFacultad de Ciencias Qu\u00edmicas y Farmac\u00e9uticas
\nUniversidad de Chile<\/p>\n

Presentaciones en Poster
\nNacionales
\n-Regulaci\u00f3n de la Expresi\u00f3n del Receptor Tipo Toll 4 (TLR4) por el Factor de Necrosis Tumoral \u03b1 y Dexametasona. Ram\u00f3n P\u00e9rez, Rodrigo Valenzuela, Enzo Candia y Marcela Hermoso. XXI Reuni\u00f3n Anual de la Sociedad de Biolog\u00eda Celular de Chile, Puc\u00f3n, Chile, 2007.<\/p>\n

-Regulaci\u00f3n negativa end\u00f3gena de la respuesta Inmune Innata mediada por los Toll-like Receptors (TLRs): Papel de los glucocorticoides. Ram\u00f3n P\u00e9rez, Rodrigo Valenzuela, Sof\u00eda Sep\u00falveda, Frano Malinarich, Enzo Candia y Marcela A. Hermoso. Presentaci\u00f3n ICBM, Facultad de Medicina, Universidad de Chile, Septiembre, 2007.<\/p>\n

Internacionales
\n-Regulation of the Toll-Like Receptor 4 (TLR4) expression by Tumor Necrosis Factor \u03b1 and Dexamethasone. R. D. P\u00e9rez, R. Valenzuela, A. Paredes, M. A. Hermoso. International Congress of Immunology, Rio de Janeiro, Brazil, 2007.<\/p>\n

-Isolation of genes with asymmetric expression in the zebrafish brain. Alicia Colombo, Marina Mione, R. D. P\u00e9rez, Stephen Wilson and Miguel Concha. International Congress of Development Biology, Buenos Aires, Argentina, 2008.<\/p>\n

-Identification of genes with asymmetric expression in the zebrafish brain. Alicia Colombo, Marina Mione, R. D. P\u00e9rez, Mauricio Gonzalez, Andr\u00e9s Aravena, Stephen Wilson and Miguel Concha. Internacional Society of Developmental Biologists Congress, Edinburgh, UK, 2009.<\/p>\n

-Dyrk1a and DSCR1 are overexpressed in neuronal cell lines derived from the cerebral cortex and hippocampus of a trisomy 16 mouse, an animal model of Down syndrome, C. Arriagada, R. D. P\u00e9rez, A.M. C\u00e1rdenas, J. Segura-Aguilar, R. Caviedes, P. A. Caviedes. Annual Meeting of Society for Neuroscience, Chicago, US, 2009.<\/p>\n

-Knockdown of Rcan1 and Dyrk1A ameliorate the cholinergic dysfunction in cell lines derived from the cerebral cortex of a Ts16 mouse, a model of Down syndrome: Possible role of VaChT and CHT1 proteins as targets, Noriega J, Acu\u00f1a M, P\u00e9rez-N\u00fa\u00f1ez R, C\u00e1rdenas AM, Segura-Aguilar J, Caviedes R, Lockman P, Caviedes P., Annual Meeting of Society for Neuroscience, Washington DC., US, 2011.
\n-RCAN1 overexpression results in enhanced voltage-gated calcium currents via impairment of inactivation in a neuronal cell line derived from cerebral cortex of Ts16 mice, an animal model of Down Syndrome, Acu\u00f1a M, Noriega J, Perez-N\u00fa\u00f1ez R, Segura-Aguilar J, Bacigalupo J, Delgado R, Cardenas AM, Caviedes R, Caviedes P., Annual Meeting of Society for Neuroscience, Washington DC., US, 2011.<\/p>\n

-Knockdown of Rcan1 and Dyrk1A recover cholinergic function in cortex cell lines derived from the Ts16 mouse, a model of Down syndrome, Noriega J, Acu\u00f1a M, P\u00e9rez-N\u00fa\u00f1ez R, C\u00e1rdenas AM, Segura-Aguilar J, Caviedes R, Caviedes P., V Neurotixicity Society Meeting, Uspallata, Argentina, 2011.<\/p>\n

-Overexpressed RCAN1 Underlies alterations in calcium currents in a neuronal cell line derived from the cerebral cortex of a trisomy 16 mouse, a model of down syndrome, Acu\u00f1a M, Noriega J, P\u00e9rez-Nu\u00f1ez R, C\u00e1rdenas AM, Segura-Aguilar J, Caviedes R, Caviedes P., V Neurotixicity Society Meeting, Uspallata, Argentina, 2011.<\/p>\n

-Gene knockdown as a strategy to dissect specific neuronal dysfunction in vitro models of down syndrome, P\u00e9rez-Nu\u00f1ez R, Acu\u00f1a M, Noriega J, Arriagada C, C\u00e1rdenas AM, Segura-Aguilar J, Caviedes R, Caviedes P., Symposium: Neurotoxicity and Neuroprotection, V Neurotoxicity Society Meeting. Uspallata, Argentina, 2011.<\/p>\n

-Increased expression of DSCAM and its action on neuronal morphological parameters in immortalized cell models of Down Syndrome. Possible role of the PAK effector pathway, R. D. P\u00e9rez, J.V. Barnier, R. Caviedes, A. C\u00e1rdenas, P. A. Caviedes. Annual Meeting of Society for Neuroscience, San Diego, US, 2013.<\/p>\n

-Increased expression of DSCAM and its action on neuronal morphological parameters in immortalized cell models of Down Syndrome. Possible role of the PAK effector pathway, R. D. P\u00e9rez, J.V. Barnier, R. Caviedes, A. C\u00e1rdenas, P. A. Caviedes. Annual Meeting of Society for Neuroscience, Washington DC, US, 2014.
\n_____________________________________________________________________________<\/p>\n

Publicaciones<\/p>\n

– P\u00e9rez-N\u00fa\u00f1ez R., Barraza N., Gonzalez A., C\u00e1rdenas A.M., Barnier J. y Caviedes P., Overexpressed Down Syndrome Cell Adhesion Molecule (DSCAM) Deregulates P21-Activated Kinase (PAK) Activity in na In Vitro Neuronal Modelo f Down Syndrome: Consequences on Cell Process Formation and Extension. Neurotox Res. February, 2016.<\/p>\n

-Acu\u00f1a M., P\u00e9rez-N\u00fa\u00f1ez R., Noriega J., C\u00e1rdenas AM., Bacigalupo J., Delgado R., Arriagada C., Segura-Aguilar J. Caviedes R. y Caviedes P., Altered Voltage Dependent Calcium Currents in a Neuronal Cell Line Derived From the Cerebral Cortex of a Trisomy 16 Fetal Mouse, an Animal Model of Down syndrome. Neurotox Res. Dec 28, 2011.<\/p>\n

-Alicia Colombo, Karina Palma, Lorena Armijo, Marina Mione, Iskra A. Signore, Camila Morales, N\u00e9stor Guerrero, Margarita Meynard, Ram\u00f3n P\u00e9rez, Jos\u00e9 Suazo, Katherine Marcelain, Luis Briones, Steffen H\u00e4rtel, Stephen W. Wilson y Miguel L. Concha. Daam1a mediates asymmetric habenular morphogenesis by regulating dendritic and axonal outgrowth. Development. July 8, 2013.<\/p>\n

_________________________________________________________________<\/p>\n

Asistencia Congresos<\/p>\n

2002-\u201803-\u201804 Jornadas de Investigaci\u00f3n, Facultad de Ciencias Qu\u00edmicas y Farmac\u00e9uticas,
\nUniversidad de Chile.
\n2004 Congreso de Estudiantes de Bioqu\u00edmica, Universidad de Chile.
\n2005 Congreso de Estudiantes de Bioqu\u00edmica, Universidad Andr\u00e9s Bello.
\n2007 Congreso Internacional de Inmunolog\u00eda, R\u00edo de Janeiro, Brasil.
\n2007 XXI Reuni\u00f3n Anual de la Sociedad de Biolog\u00eda Celular, Puc\u00f3n, Chile.
\n2013-\u00b414 Annual Meeting of Society for Neuroscience, US
\n_____________________________________________________________________________
\nCursos Adicionales<\/p>\n

Gen\u00e9tica Toxicol\u00f3gica, Bioqu\u00edmica III, Unidad de Investigaci\u00f3n en Inmunolog\u00eda, Transducci\u00f3n de Se\u00f1ales, T\u00e9cnicas Experimentales en Gen\u00e9tica Molecular, RadioBioqu\u00edmica, Principles of Single Molecule Biophysics and its Applications, Facultad de Ciencias Qu\u00edmicas y Farmac\u00e9uticas, Universidad de Chile, curso bioinform\u00e1tico del manejo de Ensembl, Facultad de Ciencias, Universidad de Chile.<\/p>\n

T\u00e9cnicas de Laboratorio<\/p>\n

RT-PCR en Tiempo Real, Transfecci\u00f3n transiente, InmunoWestern Blot, InmunoDot Blot, Zimograf\u00eda, Herramientas b\u00e1sicas de Bioinform\u00e1tica, Hibridaci\u00f3n in situ, Microinyecci\u00f3n, Transformaci\u00f3n de bacterias, Clonamiento en vector plasmidial, Adquisici\u00f3n y procesamiento de im\u00e1genes mediante lupa fluorescente y microscopia confocal, Manejo de l\u00edneas celulares y embriones de pez cebra, Dise\u00f1o de microarray, ELISA.
\n_____________________________________________________________________________<\/p>\n

Experiencia Laboral<\/p>\n

2008-2009 Asistente de Investigaci\u00f3n, Laboratorio de Neurobiolog\u00eda Comparada y Biolog\u00eda del Desarrollo. Facultad de Medicina, Universidad de Chile.
\n2009-2011 Asistente de Investigaci\u00f3n, Laboratorio de Terapia Celular
\nFacultad de Medicina, Universidad de Chile.
\n_____________________________________________________________________________<\/p>\n

Otros
\n– Nivel de manejo Computacional: Nivel avanzado en uso de Microsoft Office, Graphpad Prisma, Image J, GelPro, Opticon Monitor, Adobe Photoshop and Ilustrator.
\n– Lengua extranjera: Ingl\u00e9s: nivel intermedio.<\/p>\n","protected":false},"excerpt":{"rendered":"

Ram\u00f3n P\u00e9rez N\u00fa\u00f1ez – Bioquimico Grados Acad\u00e9micos 1999-2005 Estudios Universitarios Facultad de Ciencias Qu\u00edmicas y Farmac\u00e9uticas Universidad de Chile, Licenciatura en Bioqu\u00edmica. Diciembre, 2005 Grado: Licenciado en Bioqu\u00edmica 2006-2007 Memoria de T\u00edtulo \u201cRegulaci\u00f3n de la Expresi\u00f3n del Receptor Tipo Toll 4 (TLR4) por el Factor de Necrosis Tumoral \u03b1 y Dexametasona\u201d 2011-2015 Programa Doctorado en […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-89","post","type-post","status-publish","format-standard","hentry","category-expositores"],"_links":{"self":[{"href":"https:\/\/www.expofuturo.cl\/index.php\/wp-json\/wp\/v2\/posts\/89","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.expofuturo.cl\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.expofuturo.cl\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.expofuturo.cl\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.expofuturo.cl\/index.php\/wp-json\/wp\/v2\/comments?post=89"}],"version-history":[{"count":9,"href":"https:\/\/www.expofuturo.cl\/index.php\/wp-json\/wp\/v2\/posts\/89\/revisions"}],"predecessor-version":[{"id":286,"href":"https:\/\/www.expofuturo.cl\/index.php\/wp-json\/wp\/v2\/posts\/89\/revisions\/286"}],"wp:attachment":[{"href":"https:\/\/www.expofuturo.cl\/index.php\/wp-json\/wp\/v2\/media?parent=89"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.expofuturo.cl\/index.php\/wp-json\/wp\/v2\/categories?post=89"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.expofuturo.cl\/index.php\/wp-json\/wp\/v2\/tags?post=89"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}